Biotechfluidics

Fritiof Pontén, CEO, BiotechfluidicsFritiof Pontén, CEO
With the criterion to attain zero margins for error in fluidic systems within industrial facilities, the sudden formation of bubbles can disturb the flow rate in critical processes. Bringing forth a suitable solution to this expensive problem, Sweden-based Biotechfluidics provide some of the most sophisticated degassing solutions to eliminate production disruptions caused by bubbles in fluidic lines. Biotechfluidics offers original equipment manufacturers (OEM) several versions of degassers for analytical instrumentation, saving them time and money and improving the performance of its analytical instruments and chromatography.

“Biotech’s strength lies in its capability to remove all kinds of gases in solvents,” states Fritiof Ponten, CEO of Biotechfluidics.

Degassing removes gases like oxygen, nitrogen or carbon dioxide dissolved in the solvent as they detrimentally affect metallic components, especially in the semiconductor manufacturing industry, leading to reduced yield and increased corrosiveness. Biotechfluidics’ on-line degassing improves semiconductor device manufacturing and assembly processes, thereby delivering more consistent performance with a degasser included in the fluid path.

On-line degassing is achieved by passing the liquid through a gas-permeable membrane positioned in a vacuum chamber. The membrane with high gas-permeability helps attain optimum vacuum degassing performance, ensuring efficient and continuous gas removal, even if the liquids are transported through the degassing chamber at high flow rates.

Biotechfluidics’ patented degasser design consists of a gas-permeable membrane and a vacuum source that provides the driving force to remove dissolved gases from liquid flow streams. Removal of dissolved gases eliminates the root cause of bubble formation, dissolved gases, and improves volume delivery precision.

Biotechfluidics offers its DEGASi series of on-line degassers to ensure effective degassing of flowing liquids under various conditions. The highly-intuitive and efficient solutions prevent the formation of micro bubbles, which form in the process of testing reagents—dispensed at high speeds—with the help of pumps. In such scenarios, precision is the key to success. Additionally, a wide range of Biotechfluidics DEGASi degassers are extremely flexible and designed to meet several different requirements regarding volume, flow rate, and solvent compatibility. Biotechfluidics also offers a liquid flow meter that has an exceptionally high precision and integration rate. It is a cornerstone to determining the actual efficacy, output, and condition of the liquid pumps used.

  • Biotechfluidics’ strength lies in its capability to remove all kinds of gases in solvents


The company’s products help users remove dissolved gases from organic solvents, even at flow rates up to a hundred milliliters a minute. On-line degassing enhances the capability of laboratory analysis equipment such as liquid and ion chromatography, HPLC, UHPLC, and mass spectrometry. They also improve the performance of immunology, hematology, and in vitro diagnostics instruments.

With more than ten years of chromatography proficiency and finding solutions to issues with gases and bubbles in fluidic systems, Biotechfluidics has helped clients from various industries to overcome their problems. For instance, the company collaborated with a diagnostic manufacturer struggling with the issue of bubble formation in their production line. The client was dispensing biological reagents for COVID-19 testing kits, and those reagents were stored under slight nitrogen pressure and refrigerated at four degrees Celsius. However, in their manufacturing unit, the liquid warmed up on the way to the dispensing pump, and bubbles began to form. The client employed Biotechfluidics’ degassing solutions and followed the suggestions made by Pontén and his team. After a quick installation, the client observed that their equipment performed better than ever and has had no bubbling issues.

Similarly, with subsidiaries in US, and Japan, Biotechfluidics is inclined to resolve customer-specific issues in different industries and continents. Following the best and industry-appropriate practices such as durable, non-leachable, and leakage-free materials, Biotechfluidics has evolved as the go-to option for customers in liquid handling and fluid transfer components for analytical, biotech, and life science manufacturing processes across the globe.

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Company
Biotechfluidics

Management
Fritiof Pontén, CEO

Description
Biotechfluidics provides sophisticated degassing solutions to eliminate production disruptions caused by bubbles in fluidic lines. Biotechfluidics’ offers original equipment manufacturers (OEM) several versions of degassers for analytical instrumentation, saving them time and money, all while improving the performance of its analytical instruments and chromatography.

Biotechfluidics News

Improved fluidic design and efficient degassing enhance SPR instrument performance

Biotech Fluidics AB reports that it is supplying key microfluidic and degassing components to BioNavis Oy (Tampere, Finland) for its range of Multi-Parametric Surface Plasmon Resonance (MP-SPR) instruments.

Surface Plasmon Resonance (SPR) serves as a widely utilized method for assessing molecular interactions in fluidics, encompassing serum, saliva, and organic solvents. This label-free technique enables the evaluation of affinity and kinetics in molecular binding reactions. The BioNavis Navi™ series of advanced MP-SPR instruments offers superior features and performance, facilitating studies of surface interactions and nanolayer characterization. Scientists benefit from these Navi MP-SPR instruments in various applications, such as antibody characterization, drug uptake pathways, controlled drug release strategies, small molecule measurements, nanoparticle targeting, and drug internalization by living cells.

Jussi Tuppurainen, Technical Director of BioNavis, acknowledged the critical role of IDEX port selection valves supplied by Biotech Fluidics in their MP-SPR fluidics systems. These high-quality valves enable precise handling of samples, granting researchers control over timing, volume, and flow rate of injected liquids. This precision ensures reproducible results and minimizes variations in sample concentration. Furthermore, the Degasser system supplied by Biotech Fluidics effectively maintains sample integrity by preventing the introduction of disruptive air bubbles during measurements. The thoughtful fluidic design and efficient degassing techniques eliminate bubbles, preserving sample stability and ensuring reliable data.

In conclusion, Jussi Tuppurainen expressed BioNavis' long-standing satisfaction as a customer of Biotech Fluidics. The recommendation extends not only to their top-quality products but also to their consistently professional and friendly customer service.

Multilayer stainless-steel filters for elevated temperature and corrosive applications

Biotech Fluidics AB, a Swedish biotech company, has introduced a new series of multilayer stainless-steel filters designed for larger bore elevated temperature and corrosive processing applications. These Poro–Frit filters incorporate exclusive closed-edge technology, ensuring a consistent flow profile even at the edges of the filter.

The filters are available in a diverse range of diameters, spanning from 20 to 200 mm, and offer a porosity range of 2 to 20 microns. These self-standing and inherently stable multilayer sintered wire mesh filters are crafted to reduce costs by extending on-stream life and providing trouble-free service. Additionally, they are easily cleanable, contributing to reduced disposal costs.

Crafted from 316L stainless-steel, these filters are well-suited for process applications up to 600⁰C. They come passivated and are accompanied by comprehensive batch and traceability documentation.